Self-directed violence, including fatal and non-fatal suicidal behavior, is a serious public health problem affecting all ages, and exacts a high toll on everyone it touches. Populations with high rates include youth, veterans and people over the age of 65. In this opening keynote address, Dr. Wehry will highlight Maine’s unique demographics and describe the risk factors associated with suicidal behavior and how to mitigate that risk across the lifespan, with an emphasis on promoting and strengthening individual, family and community connectedness.